Interstitial nephritis induced by ciprofloxacin

We report a patient with acute interstitial nephritis induced by ciprofloxa cin. Diagnosis was made difficult in this case because of a previous episod e of acute renal failure secondary to legionella pneumonia. We describe this rare association (intestitial nephritis and ciprofloxacin) , as well as the difficult diagnosis given the prolonged anuria of the pati ent. We carried out a bibliographic search in Medline (1992-1997) and comme nt on the 26 cases published up to now. This association has to be consider ed because of the frequent use of this antibiotic.