Contemporary management of spinal osteomyelitis

OBJECTIVE: We review the results of treatment of a series of patients with spinal osteomyelitis, to formulate a systematic and comprehensive approach to the management of this disease in light of recent technical and conceptu al advances in imaging, spinal biomechanics, and internal fixation. METHODS: We retrospectively reviewed the records for 57 consecutive patient s with pyogenic spinal osteomyelitis who were treated between lune 1987 and lune 1995. Pain and weakness were the most common presenting symptoms. The mean duration of symptoms at the time of diagnosis was 10.6 weeks. Surgica l indications included the presence or development of motor deficits with e pidural compression and/or localized kyphotic deformities or the failure of medical therapy. RESULTS: Thirty-three patients underwent surgery as their initial treatment . Six additional patients experienced medical therapy failure and received subsequent surgical treatment. Seventeen patients were treated using an ant erior approach only, 13 were treated using a posterior approach only, and 9 were treated using a combined anterior and posterior approach. After a min imal follow-up period of 24 months, 93% of the surgically treated patients showed neurological improvement or were neurologically intact, with a mean 16-deguee decrease in localized kyphotic deformities and with solid bony fu sion and resolution of pain for all patients. CONCLUSION: Early surgical decompression results in vapid improvement of ne urological deficits, decreases in kyphotic deformities, and stabilization w ith bony fusion. The presence of active infection does not preclude the use of internal fixation. Nonsurgical management is indicated for patients wit h minimal or no neurological deficits and the absence of significant locali zed kyphotic deformities, However, 25% of patients who were initially treat ed nonsurgically experienced medical therapy failure and underwent surgical treatment.