Iron transport across biologic membranes

Authors
Andrews, NC Fleming, MD Gunshin, H
Citation
Nc. Andrews et al., Iron transport across biologic membranes, NUTR REV, 57(4), 1999, pp. 114-123
Citations number
95
Categorie Soggetti
Food Science/Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
NUTRITION REVIEWS
ISSN journal
00296643 → ACNP
Volume
57
Issue
4
Year of publication
1999
Pages
114 - 123
Database
ISI
SICI code
0029-6643(199904)57:4<114:ITABM>2.0.ZU;2-9
Abstract
Iron is essential for life, but is toxic in excess. Nearly all organisms ha ve therefore developed regulated mechanisms for efficient transport of iron into cells. This paper reviews the current understanding of iron transport , focusing on valuable lessons from studies of yeast iron transport and the discovery of the first mammalian transmembrane iron transporter.