Eosinophilic pustular folliculitis in infancy: Report of two new cases

Eosinophilic pustular folliculitis (EPF) is a cutaneous inflammatory follic ular disorder of unknown etiology. The diagnosis is made on the basis of cl inical and histopathologic features. We describe two patients who had recur rent episodes of pruritic follicular papular and pustular lesions on the fa ce, extremities, and trunk. The eruptions lasted for 1 month with intermitt ent remissions. Laboratory tests disclosed no infectious or parasitic etiol ogy in patient 2. In patient 1 we isolated methicillin-resistant Staphyloco ccus aureus in a blood culture. He had sepsis with lung and liver involveme nt. EPF is a self-limited dermatosis. On occasion, skin lesions may become superinfected, resulting in localized pyoderma or rarely systemic infection (sepsis). Histologically both of our patients showed a moderate mixed infl ammatory infiltrate with numerous eosinophils centered around hair follicle s. Their lesions responded well to topical corticosteroids.