STRUCTURAL AMENDMENT AND STEREOSELECTIVE SYNTHESIS OF MUTISIANTHOL

Acetoxy-3,6-dimethyl-1-indanyl)-2-methyl-1-propene synthesized from 3, 6-dimethyl-1-indanone was found to be different from mutisianthol by s pectral comparison. The presence of a high-field signal in the NMR spe ctrum of the final product and various intermediates, characteristic o f the cis-1,3-dialkylindanes but absent in the spectrum of the natural terpene, suggests a revision of the structure of mutisianthol to the trans isomer. The trans-indane which was subsequently obtained indeed exhibits data fully agreeable with mutisianthol. A similar stereochemi cal revision for jungianol is also indicated.