Apoptosis is now widely recognized as an important mode of cell death. Sinc
e the apoptotic pathway is an active process, modulation of apoptosis is im
portant in our understanding of cell pathophysiology. Recent data have show
n the inhibition of apoptosis in different cell types exposed to certain cy
tokines, Therapeutics that modulate the regulation of apoptosis provide an
opportunity for the treatment of certain diseases. There are many reviews f
or apoptosis induction and the regulators involved. The present report sele
cts important articles on the recent data showing the anti-apoptotic abilit
y of cytokines in mammalian cells, Other novel compounds showing anti-apopt
otic functions are also reviewed.