An improved method for the measurement of the angiotensin-converting enzyme inhibitor lisinopril in human plasma by stable isotope dilution gas chromatography negative ion chemical ionization mass spectrometry

Authors
Leis, HJ Fauler, G Raspotnig, G Windischhofer, W
Citation
Hj. Leis et al., An improved method for the measurement of the angiotensin-converting enzyme inhibitor lisinopril in human plasma by stable isotope dilution gas chromatography negative ion chemical ionization mass spectrometry, RAP C MASS, 13(8), 1999, pp. 650-653
Citations number
12
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
ISSN journal
09514198 → ACNP
Volume
13
Issue
8
Year of publication
1999
Pages
650 - 653
Database
ISI
SICI code
0951-4198(1999)13:8<650:AIMFTM>2.0.ZU;2-R
Abstract
An improved method for the quantitative measurement of the angiotensin-conv erting enzyme inhibitor lisinopril in human plasma is presented. The assay is based on gas chromatography/negative ion chemical ionization mass spectr ometry. The method involves solid phase extraction on C18 sorbent and deriv atization to the pentafluorobenzyl diester trifluoroacetamide derivatives. Copyright (C) 1999 John Wiley & Sons, Ltd.