Nuclear nephrourology continues to develop and expand on traditional provoc
ative physiological maneuvers, such as diuretic and captopril renography. I
n addition, newer interventions are conceived, such as aspirin renography,
which test new and fascinating aspects of renal functional reserve. Since t
he last review of this topic in 1991, nephrourologic nuclear medicine has m
ade considerable progress in diverse ways. Captopril and diuresis renograph
y have made strides in establishing greater consensus of interpretation and
procedure. Commonplace aspirin, the ubiquitous wonder drug, has revealed a
n unexpected role in renography by way of its inhibition of prostaglandin E
2. Finally, further investigations of exercise renography in essential hype
rtension have deepened the plausibility of a renal role in the etiology of
perhaps 50% of affected individuals. Copyright (C) 1999 by W.B, Saunders Co
mpany.