Citation
G. Oster et Hy. Wang, ATP synthase: two motors, two fuels, STRUCT F D, 7(4), 1999, pp. R67-R72
Citations number
25
Categorie Soggetti
Biochemistry & Biophysics
Journal title
STRUCTURE WITH FOLDING & DESIGN
ISSN journal
09692126
→ ACNP
Volume
7
Issue
4
Year of publication
1999
Pages
R67 - R72
Database
ISI
SICI code
0969-2126(19990415)7:4<R67:ASTMTF>2.0.ZU;2-R
Abstract
F0F1 ATPase is the universal protein responsible for ATP synthesis. The enz
yme comprises two reversible rotary motors: F-0 is either an ion 'turbine'
or an ion pump, and F-1 is either a hydrolysis motor or an ATP synthesizer.
Recent biophysical and biochemical studies have helped to elucidate the op
erating principles for both motors.