Five novel N,N'-bifunctional Ferrocene macrocyclic dioxotetraamines (IVa si
milar to e) were synthesised. The key step for this synthesis is the prepar
ation of mono N-functionalized macrocyclic dioxotetraamine (II). The yield
of the compound II reached 45%. It provides a simple way for synthesis of N
,N'-bifunctional macrocyclic tetraamines.