Can local therapy of the joint syndrome with dolgit cream be used as an alternative to systemic nonsteroid antiinflammatory drugs in rheumatic diseases?

Aim. The trial of therapeutic effect of local therapy with dolgit cream of the joint syndrome in rheumatoid arthritis (RA), osteoarthrosis (OA) and ju venile chronic arthritis (JCA). Materials and methods. Cream dolgit was used locally with assessment of its effect by pains at rest, movement, palpation, swelling in 169, 98 and 102 patients with RA, OA and JCA, respectively. Results. Subjective improvement was recorded in 75.6% of RA and 90% of OA p atients, objective - in 80.9 and 87.2%, respectively. The cream enables a 3 0-50% reduction in daily dose of nonsteroid antiinflammatory drugs in 1/3 a nd 1/4 OA and RA patients, respectively. In JCA patients dolgit relieved sy mptoms of local inflammation. The response was growing in combination of do lgit with dimexide or magnetotherapy. Some of the OA patients experienced l ocal skin itch which,vas not registered in children. No other side effects arose. Conclusion. Cream dolgit is effective in the treatment of joint syndrome in rheumatic patients, is well tolerated and may replace systemic nonsteroid antiinflammatory drugs in some patients.