Facile reduction of tertiary lactams to cyclic amines with 9-borabicyclo[3.3.1]nonane (9-BBN)

Authors
Collins, CJ Lanz, M Singaram, B
Citation
Cj. Collins et al., Facile reduction of tertiary lactams to cyclic amines with 9-borabicyclo[3.3.1]nonane (9-BBN), TETRAHEDR L, 40(19), 1999, pp. 3673-3676
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
19
Year of publication
1999
Pages
3673 - 3676
Database
ISI
SICI code
0040-4039(19990507)40:19<3673:FROTLT>2.0.ZU;2-G
Abstract
Various 5- and 6-membered tertiary lactams were reduced to the correspondin g cyclic tertiary amines using 2.2 to 2.5 equivalents of 9-borabicyclo[3.3. 1]nonane (9-BBN). This method is highly chemoselective and it is easy to re duce a lactam in the presence of an ester. (C) 1999 Elsevier Science Ltd. A ll rights reserved.