Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

Authors
Couve-Bonnaire, S Carpentier, JF Castanet, Y Mortreux, A
Citation
S. Couve-bonnaire et al., Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines, TETRAHEDR L, 40(19), 1999, pp. 3717-3718
Citations number
6
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
19
Year of publication
1999
Pages
3717 - 3718
Database
ISI
SICI code
0040-4039(19990507)40:19<3717:SOPADV>2.0.ZU;2-9
Abstract
4-Iodopyridines react with CO and HNEt2 or 2-BuOH/NEt3 in the presence of a catalytic amount of PdCl2(PPh3)(2) to give the corresponding alpha-keto am ides and eaters in fair to high yields. (C) 1999 Elsevier Science Ltd. All rights reserved.