The male reproductive system consists of the hypothalamus, the anterior pit
uitary gland, and the testes. Alcohol can interfere with the function of ea
ch of these components, thereby causing impotence, infertility, and reduced
male secondary sexual characteristics. In the testes, alcohol can adversel
y affect the Leydig cells, which produce and secrete the hormone testostero
ne. Studies found that heavy alcohol consumption results in reduced testost
erone levels in the blood. Alcohol also impairs the function of the testicu
lar Sertoli cells that play an important role in sperm maturation. In the p
ituitary gland, alcohol can decrease the production, release, and/or activi
ty of two hormones with critical reproductive functions, luteinizing hormon
e and follicle-stimulating hormone, Finally, alcohol can interfere with hor
mone production in the hypothalamus.