Decreased BOLD functional MR activation of the motor and sensory cortices adjacent to a glioblastoma multiforme: Implications for image-guided neurosurgery

A patient with a glioblastoma multiforme and mild sensorimotor deficits had significantly less activation of the motor and sensory cortices on the sid e with the tumor than on the contralateral side on blood oxygen level-depen dent (BOLD) functional MR images. This difference, which may be due to pres sure effects or loss of vascular autoregulation, should be considered in pr eoperative planning in which BOLD functional MR imaging is used to identify eloquent col tices to be avoided during brain tumor surgery.