Assessment of dorsal nerve root and spinal cord dorsal horn function in clinically normal dogs by determination of cord dorsum potentials

Citation
Pa. Cuddon et al., Assessment of dorsal nerve root and spinal cord dorsal horn function in clinically normal dogs by determination of cord dorsum potentials, AM J VET RE, 60(2), 1999, pp. 222-226
Citations number
20
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
AMERICAN JOURNAL OF VETERINARY RESEARCH
ISSN journal
00029645 → ACNP
Volume
60
Issue
2
Year of publication
1999
Pages
222 - 226
Database
ISI
SICI code
0002-9645(199902)60:2<222:AODNRA>2.0.ZU;2-L
Abstract
Objective-To establish normal predictive values for cord dorsum potential ( CDP) onset latency after thoracic and pelvic limb sensory or mixed nerve st imulation in adult dogs. Animals-26 clinically normal adult dogs. Procedure-Sensory nerve action potentials (SNAP) were recorded proximally f rom tibial and lateral superficial radial nerves after distal stimulation. The CDP were recorded from the L-4-L-5 interarcuate ligament for the tibial nerve and from the CT-TI interarcuate ligament for the radial nerve. Linea r regression analyses were performed for CDP onset latency, and mean +/- SD was calculated for CDP onset to peak latency differences and sensory nerve conduction velocities (SNCV). Results-For the tibial nerve, expected CDP onset latency (CDPOL) = -1.194 0.014 X pelvic limb length (mm; R-e = 0.912); CDPOL = -2.156 + 0.011 x pel vic limb/spinal length (mm; R-e = 0.911); and CDPOL = 0.941 + 2.197 X tibia l nerve SNAP latency (milliseconds; R-e = 0.903). For the radial nerve, CDP OL = -0.9 + 0.014 X thoracic limb length (mm; R-e = 0.873); and CDPOL = 1.4 54 + 1.874 X radial nerve SNAP latency (milliseconds; R-e = 0.903). Mean +/ - SD for CDP onset to peak latency difference for tibial and radial nerves was 3.1 +/- 0.3 and 3.0 +/- 0.4 milliseconds, respectively. Conclusions-Strong linear associations exist between CDPOL and a number of easily measured peripheral independent variables in dogs. There is also a n arrow range of normal values for CDP onset to peak latency differences that is independent of limb length. Clinical Relevance-CDP evaluation can be used to accurately assess function al severity and distribution of abnormalities in proximal sensory nerves, d orsal nerve roots, and spinal cord dorsal horns in dogs with suspected neur opathy, radiculopathy, or myelopathy involving the brachial or lumbosacral intumescences.