Molecular hydropathicity index: Application to a series of allosteric modulators of the M-2 receptors

Authors
Vistoli, G Pedretti, A Villa, AM Villa, L Holzgrabe, U Cambareri, A
Citation
G. Vistoli et al., Molecular hydropathicity index: Application to a series of allosteric modulators of the M-2 receptors, ANALUSIS, 27(1), 1999, pp. 32-41
Citations number
15
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALUSIS
ISSN journal
03654877 → ACNP
Volume
27
Issue
1
Year of publication
1999
Pages
32 - 41
Database
ISI
SICI code
0365-4877(199901/02)27:1<32:MHIATA>2.0.ZU;2-X
Abstract
The hydropathicity of a series of compounds active as allosteric modulators at the M-2 muscarinic receptors was calculated and projected on the molecu lar surface. An analysis of the relationships between conformational and lo cal hydropathicity properties was also performed.