M. Alonso et al., Cryopreserved arterial homografts: Preliminary results in infrageniculate arterial reconstructions, ANN VASC S, 13(3), 1999, pp. 261-267
The aim of this report is to present our preliminary experience using cryop
reserved arterial homografts in below-knee revascularization. We carried ou
t a retrospective study at the Public Health Hospital of the Servicio Galeg
o da Saude (SERGAS) from October 1995 to March 1997 in which cryopreserved
arterial homografts were used for revascularization of 17 lower limbs in 16
patients. The clinical indications were limb-threatening ischemia in 15 lo
wer extremities (7 with rest pain and 8 with ischemic ulcers or gangrene),
and large aneurysms of femoropopliteal arteries in 2. In addition, 75% of t
he patients had undergone previous surgical procedures for revascularizatio
n on the involved extremity. No patient had a suitable greater saphenous ve
in in the ipsilateral extremity and all patients required a below-knee arte
rial reconstruction procedure. There was just one runoff vessel in 11 of 17
extremities (65%). A histological exam was performed in four patients who
died (1 case) or had homograft-related complications (3 cases). The results
of this study indicated that cryopreserved arterial homografts could be a
promising alternative when below-knee revascularization is required in pati
ents lacking suitable greater saphenous vein, especially in those with limi
ted life expectancy, but despite early acceptable results, many aspects mus
t be clarified. Close follow-up is mandatory.