This case is of a man with bilateral lower-extremity ischemia and a solitar
y nonhealing ulcerated lesion of the right great toe. After revascularizati
on with an aortobifemoral bypass, his right ABI increased from 0.5 to appro
ximately 0.75, but the ulcerated toe lesion did not show signs of healing a
nd instead progressed to a deeper ulceration exposing bone. Because of pres
umptive osteomyelitis, we performed a great toe amputation, and immunohisto
chemical analysis of the lesion revealed late plaque stage mycosis fungoide
s (MF). We present this case to alert the vascular surgeon to this diagnost
ic possibility when confronted with an apparent ischemic lesion and to desc
ribe what made this particular lesion suspicious for MF. To the best of our
knowledge, this is the first case of MF presenting solely as an ischemic l
esion.