Ju. Blohmer et al., Comparison of various imaging methods with particular evaluation of Color Doppler sonography for planning surgery for breast tumors, ARCH GYN OB, 262(3-4), 1999, pp. 159-171
Objective: Color Doppler sonography (CD) was compared with other diagnostic
imaging methods [mammography (MG), breast ultrasound (US) and magnetic res
onance imaging (MRI)] in the planning of surgery for breast tumors. Materia
ls and methods: 99 patients with breast cancer and 101 with ultimately beni
gn breast lesions were examined preoperatively. The specificity and sensiti
vity were calculated, as well as the predictive values. Various qualitative
and semiquantitative CD parameters were also analysed for their diagnostic
value. Results: The sensitivity/specificity of the various methods (in %)
was: MG 85/77; US 95/80; CD 82/75, MRI 90/63. The positive predictive value
(ppv)/negative predictive value (npv) (in %) was: MG 79/83; US 81/94; CD 7
2/84; MRI 79/63. The median maximum systolic flow velocity and the resistan
ce index (RI) were significantly higher in breast cancer vessels than in be
nign lesions. The number of pulsating color pixels detected by CD was signi
ficantly higher for breast cancer. In cases of breast cancer significantly
more blood flows were detected in the body of the tumor than at its periphe
ry. Conclusion: Color Doppler sonography was not superior to other diagnost
ic methods for preoperative assessment of a breast lesion. The combination
of all diagnostic procedures gave a correct classification rate of 93.3% an
d is much better than the correct classification of any single diagnostic i
maging procedure.