Conservative treatment followed by chemotherapy with doxorubicin and ifosfamide for cervical sarcoma botryoides in young females

Sarcoma botryoides of the cervix is an extremely rare tumour and seems to b e associated with a better prognosis than its vaginal counterpart. Recent s tudies have suggested that it is possible to limit surgery to local excisio n in stage I cases. We report three cases of young subjects treated success fully with polypectomy or diathermy loop excision followed by adjuvant chem otherapy. One patient had a local recurrence which was treated with further local excision. All subjects remain alive without evidence of recurrence a nd with normal menstrual function 36, 38 and 38 months following initial di agnosis. A conservative surgical approach to early cervical sarcoma botryoi des is possible. The efficacy of adjuvant chemotherapy and the regimen of c hoice still need to be investigated.