ORAL-THERAPY WITH FLURITHROMYCIN IN EAR, NOSE AND THROAT INFECTIONS

In this study efficacy and tolerability of flurithromycin ethylsuccina te (FE) were evaluated in ear, nose and throat infections. One hundred and three patients were treated with FE tablets 375 mg 12-hourly for a mean duration of treatment of 8.2 days and they were divided into gr oups according to the pathology: pharyngitis/tonsillitis (chronic 7, a cute 38), rhinosinusitis (chronic 7, acute 12), otitis (chronic 6, acu te 32) and sialadenitis (acute 1). Patients evaluable for clinical eff icacy were 101, among them a complete recovery was registered in 88.2% , an improve ment in 9.9% and a treatment failure in 1.9%, Bacteriolog ical evaluation was possible in 95 patients, showing the eradication o f the pathogen in 94.7%, Tolerability was judged to be excellent in 81 .6%, good in 15.5% and discrete in 2.9%. These results demonstrate tha t FE is safe and effective in the treatment of infections established on acute or chronic inflammatory states.