Gh. Eltabbakh et al., The combination paclitaxel, carboplatin and megestrol acetate is effectivein women with recurrent uterine papillary serous adenocarcinoma, EUR J GYN O, 20(1), 1999, pp. 18-19
Uterine papillary serous adenocarcinoma is an uncommon and very aggressive
type of endometrial cancer. A 70-year-old patient diagnosed with recurrent
uterine papillary serous adenocarcinoma was prescribed megesterol acetate (
160 mg daily), paclitaxel (135 mg/m(2)) and carboplatin (area under the con
centration-time curve of 5) every 4 weeks for 4 courses. She demonstrated c
omplete clinical response that was maintained for longer than 6 months with
minimal toxicity. The combination megesterol acetate, paclitaxel and carbo
platin may be effective in women with recurrent uterine papillary serous ad
enocarcinoma.