We present a new method for estimation of spectrum transition of nonstation
ary signals in cases of low signal-to-noise ratio (SNR). Instead of the bas
ic functions employed in the previously proposed time-varying autoregressiv
e (AR) modeling, we introduce a spectrum transition constraint into the cos
t function described by the partial correlation (PARCORR) coefficients so t
hat the method is applicable to noisy nonstationary signals of which spectr
um transition patterns are complex. By applying this method to the analysis
of vibration signals on the interventricular septum (IVS) of the heart, no
ninvasively measured by the novel method developed in our laboratory using
ultrasonics, the spectrum transition pattern is clearly obtained during one
cardiac cycle for normal subjects and a patient with cardiomyopathy.