Eighty-one cases of typhoid enteric perforation were studied prospectively
after separating them into four groups. Group A patients were treated with
resection anastomosis, group B by debridement of margins of the perforation
/wedge excision and simple closure, group C by simple closure and group D b
y ileostomy of perforated ileum or simple peritoneal drainage. A copious la
vage of the peritoneal cavity with normal saline was performed in all four
groups. The complication and mortality rates for group A patients were 37.5
0% and 21.47%, respectively, very much less than that observed in the other
three groups. The ideal treatment for typhoid enteric perforation was foun
d to be resection-anastomosis with copious peritoneal lavage.