Like the Stage 1 Disinfectants/Disinfection By-products Rule, the Interim E
nhanced Surface Water Treatment Rule (IESWTR) grew out of the negotiated ru
lemaking the US Environmental Protection Agency convened in 1992-93 under t
he Federal Advisory Committee Act (FACA). The rulemaking sought to develop
a consensus approach to simultaneously addressing potential health risks po
sed by disinfection by-products (DBPs) and waterborne pathogens. Even thoug
h the process was complicated by (1) the possibility of malting inadvertent
risk-risk tradeoffs between protection from DBPs and protection from patho
gens and (2) uncertainties affecting the assessment of both risks, the regu
latory-negotiations committee was able to devise a well-balanced, staged ap
proach to regulation. A second FACA committee finalized the approach in 199
6-97. This article summarizes the microbial side of the benefit-cost analys
is and the explicit uncertainty analysis that was used to inform the shareh
olders and the negotiators.