The effect of creatine (Cr) supplementation on muscle isometric torque gene
ration and relaxation was investigated in healthy male volunteers. Maximal
torque (Tmax), contraction time (CT) from 0.25 to 0.75 of Tmax, and relaxat
ion time (RT) from 0.75 to 0.25 of Tmax were measured during 12 maximal iso
metric 3-s elbow flexions interspersed by 10-s rest intervals. Between the
pretest and the posttest, subjects ingested Cr monohydrate (4 x 5 g/day; n
= 8)or placebo (n = 8) for 5 days. Pretest Tmax, CT, and RT were similar in
Cr and placebo groups. Also in the posttest, Tmax and CT were similar betw
een groups. However, posttest RT was decreased consistently by similar to 2
0% (P < 0.05) in the Cr group from the first to the last of the 12 contract
ions. In addition, the mean decrease in RT after Cr loading was positively
correlated with pretest RT (r = 0.82). It is concluded that Cr loading faci
litates the rate of muscle relaxation during brief isometric muscle contrac
tions without affecting torque production.