Three infrared CO2 analyzers were tested for the effect of background gases
: the Ametek CD-3A (Ametek, Thermox Instruments Division, Pittsburgh, PA),
the Drager Multiwarn P CO2 (Drager, Lubeck, Germany), and the Servomex 1440
(Servomex, Crowborough, East Sussex, UK). Various CO2 concentrations were
prepared with Wosthoff precision pumps (H. Wosthoff, Bochum, Germany). Cali
bration with a different background gas (O-2 or N-2) caused a similar but s
ystematic error in the CO2 readings of all three analyzers. When the CO2 an
alyzers were calibrated with N-2 as the background gas, the CO2 reading in
an O-2-enriched atmosphere was 8% lower than the true value. Conversely, ca
libration with O-2 as the background gas resulted in a 10% overestimation o
f CO2 levels when N-2 was the background gas. This error may be important i
n a few fields of respiratory physiology.