Ww. Campbell et al., Effects of resistance training and chromium picolinate on body compositionand skeletal muscle in older men, J APP PHYSL, 86(1), 1999, pp. 29-39
The effects of chromium picolinate (CrPic) supplementation and resistance t
raining (RT) on skeletal muscle size, strength, and power and whole body co
mposition were examined in 18 men (age range 56-69 yr). The men were random
ly assigned (double-blind) to groups (n = 9) that consumed either 17.8 mu m
ol Cr/day (924 mu g Cr/day) as CrPic or a low-Cr placebo for 12 wk while pa
rticipating twice weekly in a high-intensity RT program. CrPic increased ur
inary Cr excretion similar to 50-fold (P < 0.001). RT-induced increases in
muscle strength (P < 0.001) were not enhanced by CrPic. Arm-pull muscle pow
er increased with RT at 20% (P = 0.016) but not at 40, 60, or 80% of the on
e repetition maximum, independent of CrPic. Knee-extension muscle power inc
reased with RT at 20, 40, and 60% (P < 0.001) but not at 80% of one repetit
ion maximum, and the placebo group gained more muscle power than did the Cr
Pic group (RT by supplemental interaction, P < 0.05). Fat-free mass (P < 0.
001), whole body muscle mass (P < 0.001), and vastus lateralis type II fibe
r area (P < 0.05) increased with RT in these body-weight-stable men, indepe
ndent of CrPic. In conclusion, high-dose CrPic supplementation did not enha
nce muscle size, strength, or power development or lean body mass accretion
in older men during a RT program, which had significant, independent effec
ts on these measurements.