C-13 deisopropylated and/or C-7 oxidized resin acid derivatives were tested
against various microorganisms to determine structural features responsibl
e for biological activity and to determine the influence of the C-13 isopro
pyl group on antimicrobial activity. Test results show that methyl cis and
trans 7-oxo-13-deisopropyldehydroabietate and a mixture of both isomers exh
ibited activity against fungi and bacteria. (C) 1999 Elsevier Science B.V.
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