Short note: Melatonin-dependent infertility

Melatonin may be a key factor in the regulation of seasonal variation in go nadal activity. The circadian disturbances related to reproduction are prob ably subsequent to the seasonal change. Moreover, melatonin might also be c onsidered essential for both spermatogenesis and folliculogenesis. Exposure to bright light, suppressing the concentration of melatonin in circulation , is hypothesized to be useful in treatment of both male and female inferti lity in couples with abnormal melatonin metabolism.