Microbiological and clinical effects of a 1% chlorhexidine-gel in untreated periodontal pockets from adult periodontitis patients

The aim of this study was to report the microbiological and clinical effect s of repeated subgingival administration of a 1% Chlorhexidine-gel in perio dontal pockets from 10 patients with adult periodontitis. Results showed that the experimental treatment significantly improved clini cal parameters (Plaque Index, Gingival Bleeding Index, and Pocket Probing D epth). Direct subgingival administration of Chlorhexidine-gel also produced a remarkable modification in the proportions of putative periodontopathic microorganisms, such as Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Veillonella parvula, Fusobacterium nucl eatum, and Peptostreptococcus micros, in subgingival bacterial plaque from periodontitis patients.