N-acyl-alpha-triphenylphosphonioglycinates: A novel cationic glycine equivalent and its reactions with heteroatom nucleophiles

Authors
Mazurkiewicz, R Grymel, M
Citation
R. Mazurkiewicz et M. Grymel, N-acyl-alpha-triphenylphosphonioglycinates: A novel cationic glycine equivalent and its reactions with heteroatom nucleophiles, MONATS CHEM, 130(4), 1999, pp. 597-604
Citations number
22
Categorie Soggetti
Chemistry
Journal title
MONATSHEFTE FUR CHEMIE
ISSN journal
00269247 → ACNP
Volume
130
Issue
4
Year of publication
1999
Pages
597 - 604
Database
ISI
SICI code
0026-9247(199904)130:4<597:NANCGE>2.0.ZU;2-#
Abstract
Two simple and convenient methods of transforming easily accessible 4-phosp horanylidene-5(4H)-oxazolones into N-acyl-alpha-triphenylphosphonioglycinat es are described. N-Acyl-alpha-triphenylphosphonioglycinates react smoothly with heteroatom nucleophiles in the presence of DBU or triethylamine yield ing the corresponding alpha-functionalized glycine derivatives.