Complex regional pain syndrome (CRPS) remains a poorly understood chronic p
ain disorder. Little data has been published assessing the epidemiology of
CRPS (and reflex sympathetic dystrophy, RSD). This study assessed epidemiol
ogical variables in 134 CRPS patients evaluated at a tertiary chronic pain
clinic in the US, including demographic, health care utilization and legal/
workman's compensation measures. In addition, the frequency of physician-im
posed immobilization of the CRPS limb was assessed, as was physical examina
tion evidence of myofascial dysfunction. This study found that these patien
ts had seen on average 4.8 different physicians before referral to the pain
center and had received an average of five different kinds of treatments b
oth prior to and during pain clinic treatment. The mean duration of CRPS sy
mptoms prior to pain center evaluation was 30 months. Seventeen percent had
a lawsuit and 54% had a worker compensation claim related to the CRPS. Fif
ty-one patients received a bone scan, but only 53% of which were interprete
d as consistent with the diagnosis of RSD/CRPS. Forty-seven percent had a h
istory of physician-imposed immobilization, and 56% had a myofascial compon
ent present at evaluation. The duration of CRPS symptoms and the involvemen
t of the upper extremity was significantly associated with the presence of
myofascial dysfunction. Thus, this study found that most CRPS patients are
referred to a pain specialty clinic after several years of symptoms and man
y failed therapies. The data also suggest the lack of utility of a diagnost
ic bone scan and highlight the prominence of myofascial dysfunction in a ma
jority of CRPS patients. (C) 1999 International Association for the Study o
f Pain. Published by Elsevier Science B.V.