The authors describe a 7-year-old Chinese-American female with a germinoma
of the basal ganglia who presented with progressive hemiparesis and cerebra
l hemiatrophy. The additional finding of markedly elevated antiphospholipid
antibodies suggests the possibility of an autoimmune pathogenesis for the
progressive cerebral atrophy, as well as the later development of cognitive
decline, ties, and obsessive-compulsive behaviors. (C) 1999 by Elsevier Sc
ience Inc, All rights reserved.