C. Londos et al., Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells, SEM CELL D, 10(1), 1999, pp. 51-58
Although all animal cells package and store neutral lipids in discrete intr
acellular storage droplets, there is little information on the molecular pr
ocesses that govern either the deposition or catabolism of the stored lipid
components. Studies on anipocytes have uncovered the perilipins and ADRP,
related proteins that appear to be intrinsic to the surfaces of intracellul
ar lipid storage droplets. We discuss the properties, distribution, localiz
ation, and potential functions of these proteins, as well as those of vimen
tin and the recently-described 'capsular' proteins, in lipid storage and me
tabolism.