Magnetic resonance (MR) imaging-guided biopsy is one of the most exciting a
nd rapidly developing areas in radiology. MRI offers the best demonstration
of many pathological lesions because of its multiplanar and three-dimensio
nal (3D) capabilities, excellent soft tissue contrast, and high spatial res
olution. This article reviews the state of the art in percutaneous MR-guide
d biopsies. Indications, technical aspects for optimal performance of the p
rocedures, and specific advantages and disadvantages are discussed. Special
emphasis is placed on the use of open MR scanners, which dramatically incr
eases patient accessibility for MR-guided biopsies. Specific topics address
ed include MR-guided biopsy of the brain, the head and neck, and of abdomin
al, breast, and musculoskeletal regions.