In this study, the cost-effectiveness of anticoagulation self-management-wh
ich is now established in Germany-was compared with the conventional method
of monitoring oral anticoagulant therapy by the patient's family physician
or by a specialist, Costs were determined based on the usual conditions in
Germany such as frequency of testing and control testing, scope of the tes
ts, and diagnostic and therapeutic standards for thromboembolic or bleeding
complications, In addition to direct monitoring costs, we determined the c
osts for treating minor and serious complications and used them to calculat
e overall therapy costs, The incidence of complications was estimated based
on the results of more recent studies, The only costs considered in this s
tudy were those covered by the primary cost carrier-the government-controll
ed health insurance funds-and included outpatient visits and, in cases of s
erious complications, acute inpatient treatment and rehabilitation. It was
shown that the costs to treat minor complications only slightly affected an
nual, overall treatment costs. The potential reduction in incidences of ser
ious bleeding and thromboembolic complications due to anticoagulation self-
management-which is independent of the indication for oral anticoagulation-
reduced overall therapy costs from DM 2,061.48/patient-year for conventiona
l therapeutic methods to DM 1,342.46/patient-year for patients under self-m
anagement of anticoagulation.