Many researchers have reported gender differences in levels of reported sym
ptoms, morbidity, mortality and medical care utilization, but the debate co
ntinues about the underlying causes of these differences. Some have argued
that women use more medical services because they are more sensitive to sym
ptoms and interested in health, while others believe that women's greater s
ervice utilization arises from the fact that women experience more morbidit
ies than do men. To date, these questions have not been studied prospective
ly. Using data from a household interview survey carried out in 1970-1971 a
nd linked to 22 years of health services utilization records, we explored t
he effects of gender, self-reported health status, mental and physical symp
tom levels, health knowledge, illness behaviors and health concerns and int
erest on the long-term use of health services. After controlling for the af
orementioned factors, female gender remained an independent predictor of hi
gher utilization over the 22-year period studied, and psychosocial and heal
th factors measured at the initial interview predicted service use even 19-
22 years later. Controlling for factors identified as likely causes of gend
er-related differences in healthcare utilization, gender remains an importa
nt predictor of medical care use before and after removing sex-specific uti
lization. In addition, the consistent predictive ability of attitudinal and
behavioral factors, combined with the finding that health knowledge did no
t predict utilization, indicates that efforts to help patients assess their
service needs should target the attitudinal and behavioral factors that va
ry with gender, rather than health-related knowledge alone. (C) 1999 Elsevi
er Science Ltd. All rights reserved.