Xn. Xue et Y. Ding, Assessing heterogeneity and correlation of paired failure times with the bivariate frailty model, STAT MED, 18(8), 1999, pp. 907-918
Citations number
22
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
We consider bivariate survival times for heterogeneous populations, where h
eterogeneity induces deviations in an individual's risk of an event as well
as associations between survival times. The heterogeneity is characterized
by a bivariate frailty model. We measure the heterogeneity effects through
deviations associated with hazard functions and an association function de
fined through the conditional hazard functions: the cross-ratio function pr
oposed by Oakes. We show how the deviation and association measures are det
ermined by the frailty distribution. A Gibbs sampling method is developed f
or Bayesian inferences on regression coefficients, frailty parameters and t
he heterogeneity measures. The method is applied to a mental health care da
ta set. Copyright (C) 1999 John Wiley & Sons, Ltd.