Domino-reaction of oxal(imidoyl)chlorides with 3-aminoisoxazoles: Regio- and stereoselective synthesis of 1,4-dihydro-imidazo[4,5-b]quinoxalines

Authors
Wuckelt, J Doring, M Langer, P Beckert, R
Citation
J. Wuckelt et al., Domino-reaction of oxal(imidoyl)chlorides with 3-aminoisoxazoles: Regio- and stereoselective synthesis of 1,4-dihydro-imidazo[4,5-b]quinoxalines, SYNLETT, (4), 1999, pp. 468-470
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
4
Year of publication
1999
Pages
468 - 470
Database
ISI
SICI code
0936-5214(199904):4<468:DOOW3R>2.0.ZU;2-1
Abstract
The reaction of pyrazole and triazole-derived dinucleophiles with oxalic ac id-bis(imidoyl)chlorides afforded the novel pyrazo[2,1-b]imidazolidines and imidazo[2,1-c]triazoles, respectively. The use of 3-aminoisoxazoles result ed in a domino reaction leading to biologically relevant 1,4-dihydro-imidaz o[4,5-b]quinoxalines.