Enantioselective synthesis of anti 1,3-diols via Ru(II)-catalyzed hydrogenations

Citation
D. Blanc et al., Enantioselective synthesis of anti 1,3-diols via Ru(II)-catalyzed hydrogenations, SYNLETT, (4), 1999, pp. 480-482
Citations number
33
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
4
Year of publication
1999
Pages
480 - 482
Database
ISI
SICI code
0936-5214(199904):4<480:ESOA1V>2.0.ZU;2-9
Abstract
The homogeneous ruthenium-catalyzed hydrogenation of new symmetrical 1,3-di ketones has been achieved with various ligands including SKEWPHOS and Me-Du PHOS. Complete conversions with enantiomeric and diastereomeric excesses up to 99% were obtained. This represents a new catalytic application of the c hiral ligands above.