The time to the ancestor along sequences with recombination

Authors
Citation
Rc. Griffiths, The time to the ancestor along sequences with recombination, THEOR POP B, 55(2), 1999, pp. 137-144
Citations number
13
Categorie Soggetti
Biology,"Molecular Biology & Genetics
Journal title
THEORETICAL POPULATION BIOLOGY
ISSN journal
00405809 → ACNP
Volume
55
Issue
2
Year of publication
1999
Pages
137 - 144
Database
ISI
SICI code
0040-5809(199904)55:2<137:TTTTAA>2.0.ZU;2-C
Abstract
In a sample of DNA sequences where recombination can occur to the ancestors of the sample, distinct parts of the sequences may have different most rec ent common ancestors. This paper presents a Markov chain Monte Carlo algori thm for computing the expected time to the most recent common ancestor alon g the sequences, conditional on where the mutations occur on the sequences. (C) 1999 Academic Press.