This contribution aims to introduce the readership into the fundamental mus
cle biological mechanisms (muscle composition, early post mortem muscle met
abolism, effects of connective tissue, myofibrillar density, myofibrillar p
roteolysis) determining potential tenderness of meat of various species. Th
e impact of these factors as well as those during meat processing on muscle
ultrastructural features are also briefly described. In addition, various
technological and biotechnological factors "from conception to consumption"
(including domestic preparation practices) affecting meat tenderness as pe
rceived by the consumer are summarized.