Inmates accepting high dose (greater than or equal to 60 mg) and low dose m
ethadone therapy were identified between 1/1/96 and 7/31/97 in New York Cit
y's Correctional system. We studied the duration between release to the com
munity from the first incarceration in the study period until reincarcerati
on or study's end to assess the impact of the higher dose on the criminal r
ecidivism rate. inmates discharged on high dose methadone were less likely
to return to jail than were those on low dose (P<.002) with median time to
reincarceration of 253 and 187 days respectively. Controlling for age, gend
er and race, a Cox proportional hazard model demonstrated a 13% reduction i
n hazard for reincarceration for those electing high dose. While a fixed hi
gher dose demonstrably reduced recidivism, we advocate routine methadone pl
asma level monitoring to adjust doses to achieve "blocking dose plasma leve
ls" both in the general community and the jail.