Additional reduction in blood pressure after cholesterol-lowering treatment by statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril)

Blood pressure (BP) reduction was compared between patients receiving angio tensin-converting enzyme inhibitors alone and patients receiving these medi cations plus statins after 3 months of dietary intervention. Although BP wa s similarly reduced at week 4, the statin-treated group had a greater reduc tion in BP and total cholesterol levels at week 16, suggesting a synergisti c effect between cholesterol lowering with statins and angiotensin-converti ng enzyme inhibitor treatment for hypertensive patients.