Regression of acromegalic left ventricular hypertrophy after lanreotide (aglow-release somatostatin analog)

A group of 13 acromegalic patients was treated with lanreotide for Is month s and followed-up echocardiographically; these patients showed significant correlations between the decrease of both growth hormone (GH) and insulin-l ike growth factor-1 and the decrease of left ventricular mass index. This d ocuments a regression of left ventricular hypertrophy in acromegaly after l anreotide treatment, the degree of which is dependent on the magnitude of t he decrease of GH and insulin-like growth factor-1 serum levels.