Interstitial nephritis and uveitis syndrome presenting with bilateral optic disk edema

PURPOSE: To report a rare presentation of the tubulointerstitial nephritis and uveitis syndrome. METHOD: Case report, A 34-year old woman underwent extensive clinical and l aboratory evaluation of bilateral intermediate uveitis and optic nerve edem a, RESULTS: Laboratory evaluation and nephrology consultation led to a diagnos is of tubulointerstitial nephritis, The condition resolved with the use of topical and systemic corticosteroids and the discontinuation of ibuprofen, CONCLUSIONS: Tubulointerstitial nephritis and uveitis syndrome is uncommon. It may present with anterior or intermediate uveitis. Chronic intermediate uveitis can cause optic nerve and macular edema, A thorough medical evalua tion of any patient presenting with uveitis and systemic disease is essenti al to the diagnosis and management of uveitis. (C) 1999 by Elsevier Science Inc, All rights reserved.