Medical problems in adult women with Turner's syndrome

Turner's syndrome, the most common chromosome abnormality in females, is th e consequence of complete absence or partial deletion of one X chromosome. It is associated with a wide spectrum of clinical features of which short s tature and gonadal dysgenesis are almost invariably present. Women with Tur ner's syndrome have a reduced life expectancy primarily as a result of card iovascular disease. They are also susceptible to a number of other disorder s including autoimmune thyroiditis, osteoporosis, renal and gastrointestina l disease. Thus, women with Turner's syndrome should be followed up by a mu ltidisciplinary team of physicians with an interest in the disorder followi ng discharge from paediatric care. This review aims to highlight the proble ms associated with Turner's syndrome in adulthood and to discuss important management strategies.