O-15 water positron emission tomography in language localization: A study comparing positron emission tomography visual and computerized region of interest analysis with the Wada Test

Authors
Hunter, KE Blaxton, TA Bookheimer, SY Figlozzi, C Gaillard, WD Grandin, C Anyanwu, A Theodore, WH
Citation
Ke. Hunter et al., O-15 water positron emission tomography in language localization: A study comparing positron emission tomography visual and computerized region of interest analysis with the Wada Test, ANN NEUROL, 45(5), 1999, pp. 662-665
Citations number
20
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
ANNALS OF NEUROLOGY
ISSN journal
03645134 → ACNP
Volume
45
Issue
5
Year of publication
1999
Pages
662 - 665
Database
ISI
SICI code
0364-5134(199905)45:5<662:OWPETI>2.0.ZU;2-J
Abstract
We compared O-15 water positron emission tomography (PET) auditory and visu al confrontational naming activation with an intracarotid amobarbital (Amyt al) injection procedure (IAP) for language lateralization in 12 patients wi th intractable epilepsy. PET scans were evaluated by three raters experienc ed in functional imaging as well. as by a region of interest (ROI) approach . Compared with IAP, raters' positive predictive value for language lateral ization ranged from 88 to 91%. ROI analysis had a positive predictive value of 80%. Six patients had surgery; 1 with right-sided IAP language dominanc e but left-sided PET activation had dysphasia for 6 months after left tempo ral lobectomy.